Pregnancy MRI Study
This research project seeks to map the development of functional connections within the brain of the human fetus. In particular, our aim is to establish the sequence and patterning of fetal functional neural networks. Participants in our study are healthy expecting mothers in addition to those experiencing complications with their pregnancies, such as Intrauterine Growth Restriction and Preterm Premature Rupture of Membranes. We seek to establish a link between fetal brain development and both environmental and biological factors in a babies’ early years that impact their health and growth. Our approach is to use functional (resting-state) and structural (DTI) neuroimaging methods to model healthy and atypical brain development in utero.
Seshamani, S., Fogtmann, M., Cheng, X., Thomason, M.E., Gatenby, C., Studholme, C. (2013) Cascaded Slice to Volume Registration for Moving Fetal fMRI. International Symposium on Biomedical Imaging: From Nano to Macro Conference Abstracts.
Thomason, M.E., Dassanayake, M.T., Shen, S., Katkuri, Y., Alexis, M., Anderson, A.L., Yeo, L., Mody, S., Hernandez-Andrade, E., Hassan, S.S., Studholme, C., Jeong, J.W., & Romero, R. (2013) Cross-hemispheric functional connectivity in the human fetal brain. Science Translational Medicine. 5(173):17324.
Anderson, A.L., & Thomason, M.E. (in press) Functional plasticity before the cradle: A review of neural functional imaging in the human fetus. Neuroscience & Biobehavioral Reviews.
Feng, W., Neelavalli, J., Haacke, E.M., Hamtaei, R., Katkuri, Y., Xuan, Y., Latif, Z., & Thomason, M.E. (2012) Measuring flow in the umbilical cord vessels using non-gated phase contrast MRI. Presented at the Radiological Society of North America 98th Annual Meeting in November 2012.
Schaffhauser, J., Baldwin, G., Lozon, T.A., Rihan, B., Quednau, K.A., Shen, S., Katkuri, Y., Goetz, S., Carre, J.M., Marusak, H.A., & Thomason, M.E. (2012) Hippocampal to default mode network (DMN) neural connectivity corresponds to cortisol levels during MRI in youth. Society for Neuroscience 42nd Annual Meeting Abstracts.
Seshamani, S., Fogtmann, M., Thomason, M.E., & Studholme, C. (2012) Resting state analysis of function in the moving fetal brain? International Society for Magnetic Resonance in Medicine.
Neelavalli, J., Yeo, L., Mody, S., Thomason, M.E., Singh, R.B., Haacke, E. M., & Romero, R. (2012) Magnetic resonance venography of the fetal brain using susceptibility weighted imaging at 1.5T and 3.0T: Preliminary results. Inaugural Pacific Rim Congress: Ultrasound and Magnetic Resonance Imaging of the Fetus.
Welsh, R., Nemec, U., & Thomason, M.E. (2011) Fetal magnetic resonance imaging at 3Tesla. Topics in Magnetic Resonance Imaging. (22):119-131.